Although this is a condition with many potential patients, we had no information regarding patient profiles for those visiting hospitals (severe disease) vs our recruitment targets (mild to moderate disease). We ran a pilot plan to test our hypothesis, then used the results to characterize the second screening. The recruitment plan was modified twice during the period. Through strategic planning and optimization, we achieved 115% of the achievement target within 4 months.

Overactive bladder is a condition that many patients are embarrassed to discuss openly. 3H developed a multi-channel approach combining digital outreach with our established patient database to identify and engage eligible participants. Our call center team provided sensitive, trained communication to support conversion from inquiry to referral.

Oncology trials present a unique challenge — patients are often emotionally vulnerable and already undergoing treatment. 3H's Oncolo platform, with over 200,000 monthly pageviews, provided a targeted channel to reach cancer patients actively seeking clinical trial information. Our specialist team provided empathetic, knowledgeable communication throughout the recruitment process.

Rare disease recruitment requires deep community engagement and access to specialist patient networks. Through our RareS. platform — Japan's dedicated rare disease information site — and in collaboration with Genequest, 3H established a patient registry for IBD that dramatically accelerated identification of eligible participants for clinical trials.